Biochemical Pathways : Mapping Metabolic Processes

$244.99
Author Mark Terry
Binding Hardback
ISBN 9798897070381
Language English
Pages 329
Subject Category Biochemistry
Year of Publication 2026
Category:

Biochemical Pathways offers a comprehensive and systematic exploration of the chemical networks that sustain life, serving as an essential guide for students and researchers navigating the complex landscape of cellular metabolism. The book begins by establishing fundamental “Principles of Metabolic Organization,” providing readers with a solid foundation in energy transformation, thermodynamic principles, and the sophisticated balance between catabolic and anabolic processes. This introductory section carefully explains the roles of ATP as the universal energy currency and redox cofactors as essential electron carriers, while introducing the concept of metabolic compartments within the cell. The core of the text presents a detailed examination of the major metabolic pathways, organized into coherent sections that build upon one another in logical progression. The journey through “Carbohydrate Metabolism” covers everything from the fundamental steps of glycolysis and gluconeogenesis to the specialized pathways of glycogen metabolism and the pentose phosphate pathway. The exploration of “Lipid Metabolism” provides comprehensive coverage of fatty acid oxidation and synthesis, along with the complex processes of cholesterol metabolism and membrane lipid biosynthesis. The section on “Protein and Amino Acid Metabolism” delves into protein turnover, the urea cycle, and the intricate metabolic fates of individual amino acids, while “Nucleic Acid Metabolism” completes the picture with thorough explanations of nucleotide biosynthesis and degradation pathways.The book further enhances understanding through its detailed coverage of “Signal Transduction and Metabolic Control,” explaining the molecular mechanisms by which hormones such as insulin, glucagon, and epinephrine regulate metabolic flux. This section connects extracellular signals to intracellular responses, demonstrating how phosphorylation events, allosteric regulation, and changes in gene expression work together to fine-tune metabolic activity according to cellular needs. The practical relevance of these biochemical principles is powerfully demonstrated in the section “Biochemical Pathways in Health and Disease,” which examines how disruptions in metabolic pathways contribute to conditions like diabetes mellitus, atherosclerosis, cancer, and inherited metabolic disorders. These chapters effectively bridge basic science and clinical application, showing how fundamental biochemical knowledge informs modern medical practice.

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