Dermatopathology is a dynamic and essential discipline that combines microscopic expertise with clinical acumen to diagnose and classify skin disorders. From inflammatory conditions to malignant tumors, the field relies on a multifaceted approach that includes histopathology, immunohistochemistry, and molecular techniques. The dermatopathologist’s role extends beyond mere diagnosis; it encompasses prognostic assessment, therapeutic guidance, and contributions to ongoing research. As medical knowledge and technology advance, dermatopathology will remain at the forefront of ensuring that skin diseases are understood and managed with the highest level of precision, ultimately improving outcomes for patients worldwide. This book, Dermatopathology: Diagnosis of Skin Disorders, is a comprehensive exploration into the microscopic world of skin pathology, offering an in-depth understanding of skin disorders through the lens of histopathological interpretation. Designed for medical students, dermatologists, and pathologists alike, the book provides a structured approach to the diagnosis of various skin conditions by integrating clinical dermatology with detailed tissue-based analysis. As skin diseases often present with overlapping clinical features, histological examination remains a cornerstone of accurate diagnosis and effective treatment. The book guides the reader through foundational knowledge of skin anatomy and histology before delving into the pathological changes that accompany different dermatologic conditions. The content is organized to reflect the real-world diagnostic process, beginning with common inflammatory disorders, such as psoriasis, eczema, and lichen planus, followed by infectious diseases, blistering disorders, and granulomatous reactions.